The phagosomal solute transporter SLC15A4 promotes inflammasome activity via mTORC1 signaling and autophagy restraint in dendritic cells
Cynthia López‐Haber, Daniel J. Netting, Zachary Hutchins, Xianghui Ma, Kathryn E. Hamilton, Adriana R. Mantegazza
Topics & Concepts
InflammasomePhagosomeAutophagyCell biologyBiologyPhagocytosisInnate immune systemAIM2mTORC1InflammationSignal transductionImmune systemPI3K/AKT/mTOR pathwayBiochemistryImmunologyApoptosisInflammasome and immune disordersPhagocytosis and Immune RegulationAutophagy in Disease and Therapy