Stereotactic body radiation combined with oncolytic vaccinia virus induces potent anti-tumor effect by triggering tumor cell necroptosis and DAMPs
Chen Wy, Yu‐Li Chen, Han-Wei Lin, Chi-Fang Chang, Bing‐Shen Huang, Wei‐Zen Sun, Wen‐Fang Cheng
Topics & Concepts
Oncolytic virusNecroptosisVacciniaCytotoxic T cellCD8Cancer researchImmunotherapyImmunogenic cell deathVirusMedicineVirotherapyImmune systemCancer cellCancerRadiation therapyVirologyImmunologyBiologyProgrammed cell deathApoptosisIn vitroInternal medicineGeneRecombinant DNABiochemistryVirus-based gene therapy researchCancer Research and TreatmentsCAR-T cell therapy research