Interleukin-17A Promotes Human Disc Degeneration by Inhibiting Autophagy Through the Activation of the Phosphatidylinositol 3-Kinase/Akt/Bcl2 Signaling Pathway
Wen‐Si He, Ming‐Xiang Zou, Yiguo Yan, Nvzhao Yao, Wenkang Chen, Zheng Li, Wenjun Wang, Zhihua Ouyang
Topics & Concepts
AutophagyPI3K/AKT/mTOR pathwayProtein kinase BCell biologyVacuolePhosphatidylinositolLY294002Signal transductionMedicineCancer researchWestern blotChemistryBiologyBiochemistryApoptosisGeneCytoplasmSpine and Intervertebral Disc PathologySpondyloarthritis Studies and TreatmentsAutophagy in Disease and Therapy