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Recent Advances in Synthetic Methods by Photocatalytic Single-Electron Transfer Chemistry of Pyridine <i>N</i>-Oxides

Vanaparthi Satheesh, Yongming Deng

2024The Journal of Organic Chemistry15 citationsDOIOpen Access PDF

Abstract

By adoption of the enabling technology of modern photoredox catalysis and photochemistry, the generation of reactive and versatile pyridine N -oxy radicals can be facilely achieved from single-electron oxidation of pyridine N -oxides. This Synopsis highlights recent methodologies mediated by pyridine N -oxy radicals in developing (1) pyridine N -oxide-based hydrogen atom transfer catalysts for C(sp 3 )–H functionalizations and (2) β-oxyvinyl radical-mediated cascade reactions. In addition, recent research revealed that direct photoexcitation of pyridine N -oxides allowed for the generation of alkyl carbon radicals from alkylboronic acids.

Topics & Concepts

PhotocatalysisPyridineElectron transferCatalysisPhotochemistryChemistryPhotoredox catalysisNanotechnologyCombinatorial chemistryMaterials scienceOrganic chemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques
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