A comparative pilot study of oral diacerein and locally treated diacerein-loaded nanoparticles in a model of osteoarthritis
Jae Hyun Jung, Sung Eun Kim, Hak Jun Kim, Kyeongsoon Park, Gwan Gyu Song, Sung Jae Choi
Topics & Concepts
OsteoarthritisIn vivoPharmacologyPLGAChemistryTumor necrosis factor alphaProinflammatory cytokineMatrix metalloproteinaseOral administrationInflammationInterleukinIn vitroMedicineImmunologyCytokineBiochemistryPathologyBiologyBiotechnologyAlternative medicineOsteoarthritis Treatment and MechanismsInflammatory mediators and NSAID effectsChemokine receptors and signaling