A Universal DNA Aptamer that Recognizes Spike Proteins of Diverse SARS‐CoV‐2 Variants of Concern
Zijie Zhang, Jiuxing Li, Jimmy Gu, Ryan Amini, Hannah D. Stacey, Jann C. Ang, Dawn White, Carlos D. M. Filipe, Karen Mossman, Matthew S. Miller, Bruno J. Salena, Deborah Yamamura, Payel Sen, Leyla Soleymani, John D. Brennan, Yingfu Li
Abstract
Invited for the cover of this issue are John Brennan, Yingfu Li, and co-workers at McMaster University. The image depicts MSA52 as a universal DNA aptamer that recognizes spike proteins of diverse SARS-CoV-2 variants of concern. Read the full text of the article at 10.1002/chem.202200078.
Topics & Concepts
AptamerSpike (software development)Spike ProteinCover (algebra)DNASevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Computational biologyCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakBiologyGeneticsVirologyComputer scienceMedicineEngineeringMechanical engineeringPathologyOutbreakSoftware engineeringInfectious disease (medical specialty)DiseaseBacteriophages and microbial interactionsAdvanced biosensing and bioanalysis techniquesSARS-CoV-2 and COVID-19 Research