CYP3A deficiency alters bile acid homeostasis and leads to changes in hepatic susceptibility in rats
Xuan Qin, Yuanjin Zhang, Jian Lu, Shengbo Huang, Zongjun Liu, Xin Wang
Topics & Concepts
Internal medicineCYP3AEndocrinologyHomeostasisCatabolismBile acidCholesterol 7 alpha-hydroxylaseChemistrySmall intestineReceptorPregnane X receptorBiologyCytochrome P450MetabolismBiochemistryNuclear receptorTranscription factorMedicineGeneDrug Transport and Resistance MechanismsPharmacogenetics and Drug MetabolismLiver Disease Diagnosis and Treatment