Horizontal comparison of “red or blue shift” and binding energy of six fluoroquinolones: Fluorescence quenching mechanism, theoretical calculation and molecular modeling method
Haonan Lu, Zishan Li, Yongshan Zhou, Hao Jiang, Yongfeng Liu, Changchun Hao
Topics & Concepts
Chemistryvan der Waals forceQuenching (fluorescence)Hydrogen bondBovine serum albuminBinding energyFluorescenceBinding siteBinding constantLomefloxacinFluorescence spectroscopyMoleculeAbsorption spectroscopyHydrophobic effectConformational changeComputational chemistryStereochemistryOrganic chemistryChromatographyOfloxacinBiochemistryAntibioticsPhysicsQuantum mechanicsNuclear physicsCiprofloxacinProtein Interaction Studies and Fluorescence AnalysisAntibiotics Pharmacokinetics and EfficacyPhotochemistry and Electron Transfer Studies