BDNF Val⁶⁶Met polymorphism to generalized anxiety disorder pathways: Indirect effects via attenuated parasympathetic stress-relaxation reactivity.
Hsin‐An Chang, Wen‐Hui Fang, Yia‐Ping Liu, Nian‐Sheng Tzeng, Jia‐Fwu Shyu, Fang-Jung Wan, San‐Yuan Huang, Tieh-Ching Chang, Chuan-Chia Chang
Abstract
Val/Val genotype, compared to Met-carriers, may be at higher risk of GAD due to blunted vagal reactivity in response to both stress and relaxation. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
Topics & Concepts
PsychologyAnxietyReactivity (psychology)Clinical psychologyPanic disorderRelaxation (psychology)PsychopathologyGeneralized anxiety disorderAnxiety disorderInternal medicineNeurosciencePsychiatryMedicinePathologyAlternative medicineHeart Rate Variability and Autonomic ControlMental Health Research TopicsVagus Nerve Stimulation Research