Using the Secondary PH/BH Functional Groups of an Active Geminal Frustrated Lewis Pair for Carbon Monoxide Reduction and Reactions with Nitriles and Isonitriles
Jun Li, Christian Mück‐Lichtenfeld, Constantin G. Daniliuc, Gerald Kehr, Gerhard Erker
Abstract
Abstract Reaction of the secondary alkynyl(Mes*)PH phosphane 2 with (Fmes)BH 2 ⋅SMe 2 gives the geminal PH/BH frustrated Lewis pair (FLP) 3 . The PH and the BH functions are jointly used in the reduction of carbon monoxide under mild reaction conditions to give the [P]‐CH 2 ‐O‐[B] product. A subsequent cycloaddition sequence results in the liberation of formaldehyde. The FLP 3 reacts with benzonitrile to give a P‐benzamidine, and it couples two isonitriles at the FLP framework.
Topics & Concepts
GeminalChemistryFrustrated Lewis pairBenzonitrileCarbon monoxideCycloadditionMedicinal chemistryHydroxylamineLewis acids and basesOrganic chemistryCatalysisOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisSynthesis and characterization of novel inorganic/organometallic compounds