α-mangostin derivative 4e as a PDE4 inhibitor promote proteasomal degradation of alpha-synuclein in Parkinson's disease models through PKA activation
Jiayue Chen, Qi Zhu, Cui-Zan Cai, Hai‐Bin Luo, Jiahong Lu
Topics & Concepts
Alpha-synucleinParkinson's diseaseDegradation (telecommunications)Derivative (finance)ChemistryAlpha (finance)PharmacologyDiseaseBiochemistryCell biologyMedicineInternal medicineBiologyBusinessComputer scienceClinical psychologyConstruct validityPsychometricsFinanceTelecommunicationsUbiquitin and proteasome pathwaysNatural Compound Pharmacology StudiesParkinson's Disease Mechanisms and Treatments