A review of controlled release from cyclodextrins: release methods, release systems and application
Feng Yan, Shuangdi Chen, Zhaofeng Li, Zhengbiao Gu, Shude Xu, Xiaofeng Ban, Hong Yan, Cheng Li, Caiming Li
Abstract
The controlled release of guest molecules from cyclodextrin (CD) inclusion complexes is very important for specific industrial applications in foods, medicine, cosmetics, textiles, agriculture, environmental protection, and chemical materials. The term "controlled release" encompasses several related methods, including those referred to as immediate release, sustained release and targeted release. Many different CD-based controlled release systems are currently used in practical applications. CD inclusion complexes, CD coupling, supramolecular hydrogels, and supramolecular micelles are among the most common. This review systematically introduces the principles and applications of CD-based controlled release systems, providing a theoretical basis for improving the bioavailability of effective substances and broadening their range of application.