Defining the area of mitoses counting in invasive breast cancer using whole slide image
Asmaa Ibrahim, Ayat Lashen, Ayaka Katayama, Raluca Mihai, Graham Ball, Michael S. Toss, Emad A. Rakha
Abstract
was time-consuming and did not add a significant rise in overall mitotic count (P = 0.08). Using multiple HPSF, following calibration, provided the most reliable, timesaving, and practical method for mitoses counting on WSI. This study provides evidence-based methodology for defining the area and methodology of visual mitoses counting using WSI. Visual mitoses scoring on WSI can be performed reliably by adjusting the number of monitor screens.
Topics & Concepts
Grading (engineering)PathologyConcordanceDigital pathologyBreast cancerReproducibilityMedicineComputer scienceCancerMathematicsStatisticsBiologyInternal medicineEcologyBreast Cancer Treatment StudiesAI in cancer detectionCancer Genomics and Diagnostics