Fenbendazole and its synthetic analog interfere with HeLa cells’ proliferation and energy metabolism via inducing oxidative stress and modulating MEK3/6-p38-MAPK pathway
Yi Peng, Jie Pan, Fengting Ou, Wenchao Wang, Haihong Hu, Lu Chen, Su Zeng, Kui Zeng, Lushan Yu
Topics & Concepts
HeLaApoptosisCancer cellOxidative stressIn vitroIn vivoCell cultureChemistryCell biologyCancer researchBiologyPharmacologyCancerBiochemistryGeneticsBiotechnologyHistone Deacetylase Inhibitors ResearchCancer Mechanisms and TherapyPARP inhibition in cancer therapy