ATAD2 drives colorectal cancer progression by regulating TRIM25 expression via a positive feedback loop with E2F transcriptional factors
Yalin Tong, Jinbei Li, Mengle Peng, Qilan Qian, Wen Shi, Zefeng Chen, Bin Liu
Topics & Concepts
Ubiquitin ligaseCancer researchUbiquitinColorectal cancerBiologyActivator (genetics)E2FTumor progressionCell biologyCancerGeneTranscription factorGeneticsProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysCancer-related gene regulation