Highly-sensitive and homogenous detection of 8-oxoguanine based DNA oxidative damage by a CRISPR-enhanced structure-switching aptamer assay
Hao Hu, Kejun Dong, Bei Yan, Yaoqin Mu, Yangwei Liao, Lei Zhang, Songcheng Guo, Xianjin Xiao, Xinyu Wang
Topics & Concepts
AptamerCRISPRgenomic DNASpermMolecular biologyDNATrans-activating crRNAChemistryBiologyGeneGenome editingGeneticsBiochemistryAdvanced biosensing and bioanalysis techniquesCRISPR and Genetic EngineeringBiosensors and Analytical Detection