Y-box binding protein 1 (YB-1) promotes gefitinib resistance in lung adenocarcinoma cells by activating AKT signaling and epithelial–mesenchymal transition through targeting major vault protein (MVP)
Lei Lou, Juan Wang, Fengzhu Lv, Guohui Wang, Yuehong Li, Lingxiao Xing, Haitao Shen, Xianghong Zhang
Topics & Concepts
GefitinibProtein kinase BEpidermal growth factor receptorCancer researchAdenocarcinomaEpithelial–mesenchymal transitionMedicineSignal transductionInternal medicineBiologyCancerCell biologyMetastasisRNA Research and SplicingHippo pathway signaling and YAP/TAZHeat shock proteins research