Proteasomal degradation of nonstructural protein 12 by RNF114 suppresses porcine reproductive and respiratory syndrome virus replication
Yuanzhe Bai, Liwei Li, Tongling Shan, Yujiao Zhang, Xiaoyong Chen, Fei Gao, Yifeng Jiang, Yanjun Zhou, Guoxin Li, Lingxue Yu, Ning Kong, Zhiyong Ma, Guangzhi Tong
Topics & Concepts
Porcine reproductive and respiratory syndrome virusBiologyViral replicationVirologyUbiquitin ligaseArterivirusUbiquitinProteasomeVirusGene knockdownProtein degradationWestern blotCell biologyCell cultureGeneBiochemistryGeneticsCoronavirus disease 2019 (COVID-19)PathologyDiseaseMedicineInfectious disease (medical specialty)Animal Virus Infections StudiesVirus-based gene therapy researchViral gastroenteritis research and epidemiology