High-Dose Ionizing Radiation Accelerates Atherosclerotic Plaque Progression by Regulating P38/NCOA4-Mediated Ferritinophagy/Ferroptosis of Endothelial Cells
Zhinan Wu, Taiwei Chen, Yuxuan Qian, Guqing Luo, Fei Liao, Xinjie He, Wenyi Xu, Jun Pu, Song Ding
Topics & Concepts
MedicineIonizing radiationOxidative stressEndothelial dysfunctionLipid peroxidationGene knockdownReactive oxygen speciesWestern blotIn vivoEndotheliumCancer researchEndothelial stem cellPathologyIn vitroInternal medicineCell biologyIrradiationChemistryBiologyBiochemistryApoptosisBiotechnologyGeneNuclear physicsPhysicsFerroptosis and cancer prognosisChemotherapy-induced cardiotoxicity and mitigationInflammatory Biomarkers in Disease Prognosis