NCS 613, a PDE4 inhibitor, by increasing cAMP level suppresses systemic inflammation and immune complexes deposition in kidney of MRL/lpr lupus- prone mice

Issaka Yougbaré, Thérèse Keravis, Claire Lugnier

2020Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease18 citationsDOI Open Access PDF

Topics & Concepts

Lupus nephritisInflammationKidneyImmune systemSystemic lupus erythematosusNephritisSystemic inflammationInternal medicineKidney diseaseEndocrinologyMedicineImmunologyDiseasePhosphodiesterase function and regulationMast cells and histamineRenal Diseases and Glomerulopathies