Panaxytriol upregulates CYP3A4 expression based on the interaction of PXR, CAR, HSP90α, and RXRα
Lingming Zhang, Jingdi Yan, Jianming Liu, Chao Meng, Fanglan Liu, Chunhua Xia
Topics & Concepts
Pregnane X receptorCYP3A4Hsp90Retinoid X receptorNuclear receptorConstitutive androstane receptorWestern blotChemistryReceptorDownregulation and upregulationHeat shock proteinBiologyCell biologyCytochrome P450Molecular biologyBiochemistryTranscription factorMetabolismGenePharmacogenetics and Drug MetabolismHormonal Regulation and HypertensionGlutathione Transferases and Polymorphisms