Amentoflavone mitigates doxorubicin-induced cardiotoxicity by suppressing cardiomyocyte pyroptosis and inflammation through inhibition of the STING/NLRP3 signalling pathway
Guangyao Fang, Xiuchuan Li, Fengyuan Yang, Ting Huang, Chenming Qiu, Ke Peng, Ziran Wang, Yongjian Yang, Cong Lan, Cong Lan
Topics & Concepts
CardiotoxicityPyroptosisPharmacologyDoxorubicinMedicineApoptosisInflammationChemistryImmunologyInflammasomeInternal medicineToxicityBiochemistryChemotherapyChemotherapy-induced cardiotoxicity and mitigationInflammasome and immune disordersBiological Activity of Diterpenoids and Biflavonoids