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Metallacycle Expansion and Annulation: Access to <scp>Tetrazolo‐Fused</scp> Osmacycles by Reaction of Cyclic Osmium Carbyne with Sodium Azide

Hongjian Wang, Yu‐Mei Lin, Siyuan Chen, Yonghong Ruan, Haiping Xia

2021Chinese Journal of Chemistry14 citationsDOI

Abstract

Main observation and conclusion The reaction of a cyclic osmacarbyne complex with sodium azide led to the formation of a ring expansion‐annulation product, a unique tetrazole annulated polycyclic metallacycle. The reaction proceeds by insertion of a nitrogen atom into the metal carbon triple bond and the second azide participating in the [2+3] cycloaddition. The successful isolation and characterization of metalla‐azirine complex and metallapyridinium derivative strongly validated the mechanism for the formation of the title complex. The work demonstrates a new strategy to enrich the varieties of aza‐metallacyclic species.

Topics & Concepts

MetallacycleChemistryAnnulationSodium azideAzideCycloadditionTetrazoleDerivative (finance)AzirineStereochemistryCarbeneRing (chemistry)Medicinal chemistryCombinatorial chemistryOrganic chemistryX-ray crystallographyCatalysisDiffractionOpticsPhysicsEconomicsFinancial economicsClick Chemistry and ApplicationsSynthetic Organic Chemistry MethodsN-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Metallacycle Expansion and Annulation: Access to <scp>Tetrazolo‐Fused</scp> Osmacycles by Reaction of Cyclic Osmium Carbyne with Sodium Azide | Litcius