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Quantitative detection of THz-ATR spectra of aqueous samples under strong-field terahertz wave

Wei Shi, Chunhui Li, Haiqing Wang, Zhiquan Wang, Lei Yang

2022iScience15 citationsDOIOpen Access PDF

Abstract

Owing to the characteristics of THz wave, the terahertz time-domain spectral (THz-TDS) system has potentials in the field of biological macromolecule detection. However, water with strong absorption effect on THz wave exists in most biological detection, so the research focus in this field is to study aqueous samples. In view of these, THz spectroscopy system has research value for qualitative and quantitative detection of α-lactose and its water-containing samples. This research used a THz-TDS system with LiNbO3 crystal to generate strong THz wave that was used to test 0.29 mmol α-lactose samples with water content of 15 μL–930 μL by using attenuating total reflection (ATR) prism. The absorption peak at 0.53 THz is detected, and with the increase of water content, the curve of absorption spectrum is observed to move up on the whole. This research has a guiding role for the test and improvement of water content limit in this field.

Topics & Concepts

Terahertz radiationTerahertz spectroscopy and technologyPrismSpectroscopyAbsorption (acoustics)Detection limitAttenuated total reflectionAbsorption spectroscopyMaterials scienceOpticsAqueous solutionAnalytical Chemistry (journal)ChemistryOptoelectronicsPhysicsInfraredChromatographyQuantum mechanicsPhysical chemistryTerahertz technology and applicationsPlant and animal studiesSpectroscopy and Laser Applications
Quantitative detection of THz-ATR spectra of aqueous samples under strong-field terahertz wave | Litcius