Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen-induced arthritis mice
Peirong Gan, Ronghui Wang, Ran Deng, Hong Wu, Yanhong Bu, Fangyuan Chen, Xin-Tong Dong, Jiang-Tao Ke
Topics & Concepts
Macrophage polarizationSphingosine kinase 1MacrophageChemistryCell biologySphingosineSphingosine-1-phosphateReceptorCancer researchInternal medicineBiologyMedicineIn vitroBiochemistrySphingolipid Metabolism and SignalingImmune cells in cancerImmune Cell Function and Interaction