Characterization of hemocytes and hematopoietic cells of a freshwater crayfish based on single-cell transcriptome analysis
Irene Söderhäll, Erik Fasterius, Charlotta Ekblom, Kenneth Söderhäll
Abstract
to identify hitherto undescribed hemocyte types in the circulation and show that the circulating cells are more diversified than previously recognized. In addition, we discovered cell populations in the HPT with clear precursor characteristics as well as cells involved in iron homeostasis, representing a previously undiscovered cell type. These findings may improve our understanding of hematopoietic stem cell regulation in crustaceans and other animals.
Topics & Concepts
CrayfishBiologyHaematopoiesisTranscriptomeImmune systemPhagocytosisStem cellPacifastacusCell biologyCell typeCellImmunologyHemocyteImmunityMicrobiologyEcologyGeneGeneticsGene expressionInvertebrate Immune Response MechanismsAquaculture disease management and microbiotaMosquito-borne diseases and control