Recent Advances in the Synthesis of Heterocycles by the Aza-Wittig Reaction
Mohammad Mahdavi, Keyvan Pedrood, Mohammad Nazari Montazer, Bagher Larijani
Abstract
Abstract The formation of the C=N bond in recent studies on heterocyclic compounds via the aza-Wittig reaction is reviewed. Furthermore, two different strategies for the formation of heterocyclic compounds, including intermolecular and intramolecular aza-Wittig reactions are described. The primary aim of this review is to provide up-to-date information on the application of the aza-Wittig reaction in the synthesis of a wide range of N-containing heterocyclic compounds in the chemical literature since 2010. 1 Introduction 2 Mechanism of the Staudinger and Aza-Wittig Reactions 3 Intramolecular Aza-Wittig Reaction 4 Intermolecular Aza-Wittig Reaction 5 Conclusion
Topics & Concepts
Wittig reactionChemistryIntramolecular forceIntermolecular forceOrganic chemistryCombinatorial chemistryMoleculeChemical Synthesis and AnalysisClick Chemistry and ApplicationsSynthesis of heterocyclic compounds