<i>γ</i> H2AX in the S Phase after UV Irradiation Corresponds to DNA Replication and Does Not Report on the Extent of DNA Damage
Shivnarayan Dhuppar, Sitara Roy, Aprotim Mazumder
Abstract
phase. Our study suggests that it is not DNA damage, but the response elicited, which peaks in the S phase upon UV irradiation.
Topics & Concepts
DNA damagePyrimidine dimerBiologyDNA replicationDNAHistoneCyclobutaneS phaseMolecular biologyDNA repairCell cycleEukaryotic DNA replicationGeneticsBiophysicsCellChemistryRing (chemistry)Organic chemistryDNA Repair MechanismsCarcinogens and Genotoxicity AssessmentEpigenetics and DNA Methylation