Synthesis, Enzymatic Degradation, and Polymer-Miscibility Evaluation of Nonionic Antimicrobial Hyperbranched Polyesters with Indole or Isatin Functionalities
Xiaoya Li, Sedef İlk, Javier A. Linares‐Pastén, Yang Liu, Deepak Raina, Deniz Demircan, Baozhong Zhang
Abstract
, while isatin had a complex impact. Molecular docking simulations of monomeric molecules with PETase revealed different orientations of the molecules at the active site due to the presence of indole or isatin groups, which could be related to the observed different enzymatic degradation behavior. Finally, biocompatibility analysis with a mammalian cell line showed the negligible cytotoxic effect of the fabricated HBPs.
Topics & Concepts
IsatinPolyesterIndole testChemistryBiocompatibilityMiscibilityOrganic chemistryMonomerCombinatorial chemistryPolymerPolymer chemistryAntimicrobial agents and applicationsDendrimers and Hyperbranched PolymersMicroplastics and Plastic Pollution