AgNP‐decorated SBA‐15 for MWCNT Paste Modified Electrode: A Sensor for Simultaneous Voltammetric Determination of Paracetamol and Sulfamethoxazole
Oleg Tkachenko, Luana V. de Souza, Monique Deon, Emilene Becker, Eliana Weber de Menezes, Leliz Ticona Arenas, Edilson Valmir Benvenutti
Abstract
Abstract A new electrochemical sensor based on a carbon nanotube paste electrode modified with a Santa Barbara Amorphous material (SBA‐15) decorated with silver nanoparticles, namely CNT/SBA/Ag‐PE, was developed. It was successfully applied for individual and simultaneous determination of both paracetamol (PC) and sulfamethoxazole (SMZ) medicines. The electrode exhibited a linear dynamic range of 0.12–110 μmol L −1 for paracetamol and 0.06–70 μmol L −1 for sulfamethoxazole, and detection limits of 38 and 19 nmol L −1 , respectively. The proposed sensor offered high sensitivity, fast response time and the potential for detecting both drugs simultaneously. The CNT/SBA/Ag‐PE enabled the simultaneous determination of PC and SMZ in urine samples with high recovery rates.