YY1 alleviates lupus nephritis-induced renal injury by reducing the Th17/Treg cell ratio via the IFN-γ/Fra2 axis
Wang Bi, Xinhui Jiang, Yuhong Li, Haixia Xu, Bei Ying, Jie Qiu, Zhi Huang, Xiaoshan Shao
Topics & Concepts
Proinflammatory cytokineJurkat cellsLupus nephritisTumor necrosis factor alphaCancer researchInflammationT cellCytokineDownregulation and upregulationImmunologyMedicineChemistryInternal medicineImmune systemBiochemistryGeneDiseaseInflammasome and immune disordersFOXO transcription factor regulationCancer-related molecular mechanisms research