Litcius/Paper detail

Photocatalytic intermolecular <i>anti</i>-Markovnikov hydroamination of unactivated alkenes with <i>N</i>-hydroxyphthalimide

Zhipeng Ye, Yuan‐Zhuo Hu, Peng‐Ju Xia, Hao‐Yue Xiang, Kai Chen, Hua Yang

2020Organic Chemistry Frontiers31 citationsDOI

Abstract

A visible-light-induced/phosphite-promoted <italic>anti</italic>-Markovnikov hydroamination of alkenes with <italic>N</italic>-hydroxyphthalimide was successfully realized, which was initiated by a proton-coupled electron transfer to enable direct cleavage of its N–O bond.

Topics & Concepts

Markovnikov's ruleHydroaminationChemistryPhotocatalysisIntermolecular forcePhotochemistryOrganic chemistryPolymer chemistryMedicinal chemistryCatalysisMoleculeRegioselectivityRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques