Olaparib enhances curcumin-mediated apoptosis in oral cancer cells by inducing PARP trapping through modulation of BER and chromatin assembly
Sefinew Molla, Subhajit Chatterjee, Chinmayee Sethy, Saptarshi Sinha, Chanakya Nath Kundu
Topics & Concepts
OlaparibBiologyCurcuminPoly ADP ribose polymeraseChromatinApoptosisCancer researchCell biologyPARP inhibitorCancer cellCancerPharmacologyBiochemistryGeneticsDNAPolymerasePARP inhibition in cancer therapyToxin Mechanisms and ImmunotoxinsCell death mechanisms and regulation