Litcius/Paper detail

Modular design of synthetic receptors for programmed gene regulation in cell therapies

Iowis Zhu, Raymond Liu, Julie Garcia, Axel Hyrenius‐Wittsten, Dan I. Piraner, Josef Alavi, Divya V. Israni, Bin Liu, Ahmad S. Khalil, Kole T. Roybal

2022Cell194 citationsDOIOpen Access PDF

Topics & Concepts

BiologyReceptorModular designComputational biologyFunction (biology)ProteolysisSynthetic biologyGenetic enhancementCell biologyGeneComputer scienceGeneticsBiochemistryOperating systemEnzymeCAR-T cell therapy researchCRISPR and Genetic EngineeringT-cell and B-cell Immunology