Hydroxysafflor Yellow A Inhibits Aβ1–42-Induced Neuroinflammation by Modulating the Phenotypic Transformation of Microglia via TREM2/TLR4/NF-κB Pathway in BV-2 Cells
Mengqiao Ren, Mengyu Zhang, Xiaoyan Zhang, Chunhui Wang, Yanjie Zheng, Yanli Hu
Topics & Concepts
NeuroinflammationMicrogliaProinflammatory cytokineTREM2TLR4Downregulation and upregulationCell biologyNeuroprotectionNF-κBSignal transductionChemistryBiologyNFKB1PharmacologyInflammationTranscription factorImmunologyBiochemistryGeneNeuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysNeurological Disease Mechanisms and Treatments