Discovery of novel bis-evodiamine derivatives with potent antitumor activity
Huixin Liang, Wei Wang, Fugui Zhu, Shuqiang Chen, Dan Liu, Chunquan Sheng
Topics & Concepts
EvodiamineChemistryNatural productApoptosisLead compoundCell cycleStructure–activity relationshipChemical synthesisNatural compoundCell cycle checkpointStereochemistryPharmacologyCombinatorial chemistryBiochemistryIn vitroEngineeringChromatographyMedicineBiochemical engineeringQuinazolinone synthesis and applicationsSynthesis and biological activitySynthesis and Biological Evaluation