Necrostatin-1 Against Sevoflurane-Induced Cognitive Dysfunction Involves Activation of BDNF/TrkB Pathway and Inhibition of Necroptosis in Aged Rats
Chunping Yin, Qi Zhang, Juan Zhao, Yanan Li, Jiaxu Yu, Wei Li, Qiujun Wang
Topics & Concepts
SevofluraneNeuroprotectionMorris water navigation taskNecroptosisHippocampusMedicinePostoperative cognitive dysfunctionTropomyosin receptor kinase BAnesthesiaPharmacologyNeuroscienceInternal medicineNeurotrophic factorsChemistryPsychologyApoptosisProgrammed cell deathPsychiatryCognitionReceptorBiochemistryAnesthesia and Neurotoxicity ResearchIntensive Care Unit Cognitive DisordersS100 Proteins and Annexins