Litcius/Paper detail

Human PRPS1 filaments stabilize allosteric sites to regulate activity

Kelli L. Hvorecny, Kenzee Hargett, Joel Quispe, Justin M. Kollman

2023Nature Structural & Molecular Biology42 citationsDOIOpen Access PDF

Topics & Concepts

Allosteric regulationAllosteric enzymeBiophysicsActivator (genetics)RegulatorActive siteEnzymeConserved sequenceChemistryBiologyBiochemistryCell biologyDNAReceptorGeneBase sequenceBiochemical and Molecular ResearchRNA modifications and cancerAcute Lymphoblastic Leukemia research