Litcius/Paper detail

Biocatalytic cyclization of small macrolactams by a penicillin-binding protein-type thioesterase

Zachary L. Budimir, Rishi Patel, Alyssa S. Eggly, Claudia N. Evans, Hannah M. Rondon-Cordero, Jessica J. Adams, Chittaranjan Das, Elizabeth I. Parkinson

2023Nature Chemical Biology25 citationsDOIOpen Access PDF

Topics & Concepts

ThioesterasePeptideChemistryCyclic peptideAmino acidBiochemistryPeptide BiosynthesisPeptidomimeticStereochemistryCombinatorial chemistryBiosynthesisEnzymeGeneRNARibosomeBiochemical and Structural CharacterizationChemical Synthesis and AnalysisMicrobial Natural Products and Biosynthesis