A responsive AIE-active fluorescent probe for visualization of acetylcholinesterase activity<i>in vitro</i>and<i>in vivo</i>
Chunbai Xiang, Musa Dirak, Yuan Luo, Yonglin Peng, Lintao Cai, Ping Gong, Pengfei Zhang, Safacan Kölemen
Abstract
An aggregation-induced emission (AIE) active light up fluorescent probe (TCFPB-AChE) was developed for selective in vitro and in vivo imaging of acetylcholinesterase activity.
Topics & Concepts
In vivoAcetylcholinesteraseFluorescenceIn vitroBiophysicsChemistryAggregation-induced emissionAchéBiochemistryEnzymeBiologyOpticsPhysicsBiotechnologyLuminescence and Fluorescent MaterialsCholinesterase and Neurodegenerative DiseasesMolecular Sensors and Ion Detection