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Cerebellar 5HT-2A receptor mediates stress-induced onset of dystonia

Jung Eun Kim, Sujin Chae, Sungsoo Kim, Yeon‐Joo Jung, Myoung‐Goo Kang, Won Do Heo, Daesoo Kim

2021Science Advances32 citationsDOIOpen Access PDF

Abstract

mice. These results support the serotonin theory of dystonia and suggest strategies for alleviating symptoms in human patients by blocking 5HT-2A receptors.

Topics & Concepts

Dystonia5-HT receptorNeuroscienceSerotoninMedicineEndocrinologyPsychologyReceptorInternal medicineNeuroscience and Neuropharmacology ResearchGenetic Neurodegenerative DiseasesNeurological disorders and treatments