The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus
Daisuke Ono, Yasutaka Mukai, Chi Jung Hung, Srikanta Chowdhury, Takashi Sugiyama, Akihiro Yamanaka
Abstract
imaging revealed that neuronal activity of CRF neurons was negatively regulated by GABAergic neurons in the SCN. Our findings provide notable insights into circadian regulation of sleep/wakefulness in mammals.
Topics & Concepts
WakefulnessCircadian rhythmHypothalamusNeuroscienceSuprachiasmatic nucleusNucleusSleep (system call)BiologyEndocrinologyInternal medicineMedicineElectroencephalographyOperating systemComputer scienceCircadian rhythm and melatoninSleep and Wakefulness ResearchDietary Effects on Health