E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity
Daniel C. Scott, Moeko T. King, Kheewoong Baek, Clifford T. Gee, Ravi Kalathur, Jerry Li, Nicholas Purser, Amanda Nourse, Sergio C. Chai, Sivaraja Vaithiyalingam, Taosheng Chen, Richard Lee, Stephen J. Elledge, Gary Kleiger, Brenda A. Schulman
Topics & Concepts
DegronBiologyMimicryUbiquitin ligaseDNA ligaseCell biologyUbiquitinBiochemistryDNAEcologyGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments