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E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity

Daniel C. Scott, Moeko T. King, Kheewoong Baek, Clifford T. Gee, Ravi Kalathur, Jerry Li, Nicholas Purser, Amanda Nourse, Sergio C. Chai, Sivaraja Vaithiyalingam, Taosheng Chen, Richard Lee, Stephen J. Elledge, Gary Kleiger, Brenda A. Schulman

2023Molecular Cell37 citationsDOIOpen Access PDF

Topics & Concepts

DegronBiologyMimicryUbiquitin ligaseDNA ligaseCell biologyUbiquitinBiochemistryDNAEcologyGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments
E3 ligase autoinhibition by C-degron mimicry maintains C-degron substrate fidelity | Litcius