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Stop codon read-through of mammalian MTCH2 leading to an unstable isoform regulates mitochondrial membrane potential

Lekha E. Manjunath, Anumeha Singh, Sarthak Sahoo, Ashutosh Mishra, Jinsha Padmarajan, Chaithanya G. Basavaraju, Sandeep M. Eswarappa

2020Journal of Biological Chemistry38 citationsDOIOpen Access PDF

Abstract

regulates its own expression levels contributing toward the maintenance of normal mitochondrial membrane potential.

Topics & Concepts

Gene isoformStop codonBiologyUntranslated regionMitochondrionMessenger RNACell biologyGeneticsChemistryGeneRNA and protein synthesis mechanismsRNA Research and SplicingRNA modifications and cancer
Stop codon read-through of mammalian MTCH2 leading to an unstable isoform regulates mitochondrial membrane potential | Litcius