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Neurologic manifestations in an infant with COVID-19

Rachelle Dugue, Karla C. Cay-Martínez, Kiran T. Thakur, Joel A. Garcia, Lokendra V. Chauhan, Simon H. Williams, Thomas Briese, Komal Jain, Marc Foca, Danielle K. McBrian, Jennifer M. Bain, W. Ian Lipkin, Nischay Mishra

2020Neurology133 citationsDOIOpen Access PDF

Abstract

Currently, there are over 1.9 million confirmed cases of coronavirus disease 2019 (COVID-19) globally with over 590,000 cases in the United States.1 The number of COVID-19–positive children in the United States is unknown. A report summarizing 72,314 COVID-19 cases from the Chinese Center for Disease Control and Prevention noted 416 COVID-19–positive children younger than 10.2 An observational study at Wuhan Children's Hospital noted 31 COVID-19–positive children younger than 1 year with the youngest confirmed case in a 1-day-old.3 Cases were largely characterized by upper respiratory tract infection or pneumonia, fever, cough, and pharyngeal erythema.3 Concomitant neurologic problems have been reported among COVID-19–positive adult patients.4

Topics & Concepts

MedicinePediatricsConcomitantObservational studyDiseaseDisease controlRespiratory tract infectionsRespiratory tractUpper respiratory tract infectionRespiratory diseaseCentral nervous system diseaseEl NiñoYoung adultEpidemiologyCoronavirus disease 2019 (COVID-19)Long-Term Effects of COVID-19Infectious Encephalopathies and EncephalitisCOVID-19 Clinical Research Studies