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Design, docking, synthesis, and characterization of novel N'(2-phenoxyacetyl) nicotinohydrazide and N'(2-phenoxyacetyl)isonicotinohydrazide derivatives as anti-inflammatory and analgesic agents

H M Pallavi, Fares Hezam Al-Ostoot, Hamse Kameshwar Vivek, Shaukath Ara Khanum

2021Journal of Molecular Structure28 citationsDOI

Topics & Concepts

ChemistryNonsteroidalAnti-inflammatoryDocking (animal)CyclooxygenaseAnalgesicEnzymePharmacologyGene isoformStereochemistryIC50BiochemistryIn vitroNursingMedicineGeneSynthesis and biological activityInflammatory mediators and NSAID effectsSynthesis and Biological Evaluation
Design, docking, synthesis, and characterization of novel N'(2-phenoxyacetyl) nicotinohydrazide and N'(2-phenoxyacetyl)isonicotinohydrazide derivatives as anti-inflammatory and analgesic agents | Litcius