Assessment of toxicity of metal oxide and hydroxide nanoparticles using the QSAR modeling approach
Joyita Roy, Kunal Roy
Abstract
In the present study, QSAR models were developed to evaluate the cytotoxicity of MeOx NPs towards RAW 264.7 cells and to propose a short mechanism to determine the cause of cellular toxicity by the MeOx NPs.
Topics & Concepts
Quantitative structure–activity relationshipCytotoxicityToxicityMetal hydroxideNanoparticleHydroxideMetalChemistryOxideNanotechnologyMaterials scienceBiochemistryInorganic chemistryStereochemistryOrganic chemistryIn vitroNanoparticles: synthesis and applicationsElectrochemical Analysis and ApplicationsComputational Drug Discovery Methods