Ultrasmall superparamagnetic iron oxide nanoparticles for enhanced tumor penetration
Feng Xue, Yuxiang Xue, Sevil Gonca, Kunlang Ji, Mei Zhang, F.R. García–García, Quan Li, Yi Huang, Konstantin V. Kamenev, Xianfeng Chen
Abstract
nanoparticles is closely related to their cellular internalization ability. Therefore, optimization of the cellular uptake and of the magnetization of magnetic nanoparticles should be considered simultaneously for maximizing their penetration in tumor tissue through magnetophoresis.
Topics & Concepts
SuperparamagnetismMaterials scienceNanoparticlePenetration (warfare)NanotechnologyIron oxide nanoparticlesIron oxideOxideChemical engineeringMetallurgyMagnetizationOperations researchQuantum mechanicsMagnetic fieldPhysicsEngineeringNanoparticle-Based Drug DeliveryCharacterization and Applications of Magnetic NanoparticlesIron oxide chemistry and applications