Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
Lixin He, Jinxin Chen, Pinwei Deng, Shu‐Mei Huang, Pian Liu, Chanjuan Wang, Xinjian Huang, Yue Li, Boyu Chen, Dongni Shi, Yunyun Xiao, Xiangfu Chen, Ying Ouyang, Libing Song, Chuyong Lin
Topics & Concepts
BiologymTORC1Oxidative stressGlutathioneCell biologyLysosomeCancer cellAutophagyDownregulation and upregulationCancer researchHomeostasisCancerBiochemistrySignal transductionPI3K/AKT/mTOR pathwayApoptosisGeneticsGeneEnzymeBiomedical Research and PathophysiologyNeonatal Health and BiochemistryAmino Acid Enzymes and Metabolism