Testicular toxicity in cisplatin-treated Wistar rats is mitigated by Daflon and associated with modulation of Nrf2/HO-1 and TLR4/NF-kB signaling
Roland Eghoghosoa Akhigbe, Olayinka Emmanuel Adelowo, Esther Olamide Ajani, Rachael Ibukun Oyesetan, David Damola Oladapo, Tunmise Maryanne Akhigbe
Topics & Concepts
ToxicityCisplatinSignal transductionPharmacologyTLR4NF-κBChemistryCancer researchMedicineInternal medicineChemotherapyBiochemistryChemotherapy-induced organ toxicity mitigationSperm and Testicular FunctionCarcinogens and Genotoxicity Assessment